LogicSmart ZDC Virus
01 Overview
02 Details
Logix Smart™ ZDC Test Kit
The Logix Smart™ ZDC (ZIKV-DENV-CHIKV) Test kit uses our patented CoPrimer™ technology to differentiate between the ribonucleic acid (RNA) of Zika, dengue (all 4 serotypes), and chikungunya viruses and to detect and amplify regions of the viruses’ genomes.
The test operates using a single step real-time reverse transcriptase polymerase chain reaction (RT-PCR) process in serum samples, collected alongside with urine, from patients suspected of being infected with Zika, dengue, or chikungunya. The Logix Smart ZDC kit is designed and validated to identify Zika, dengue or chikungunya viruses even when more than one target is present, such as in co-infections. The presence of one target does not interfere with detection of any other targets. If a patient specimen is positive for Zika, a CSF specimen can also be collected to search for neurological infection.
- Ready-to-use Master Mix, complete with RNaseP internal positive control to verify sample quality
- Positive Control (PC), to verify the performance of the master mix
- Nuclease-Free Water as a negative control, to verify master mix is free from contamination
Intended Use
Zika virus testing is essential to aid the control and spread of the virus prior to pregnancy, transfusion, transplantation, or sexual relations. Like Zika, dengue is a mosquito borne-viral infection spread by the daytime-active Aedes mosquito species A. aegypti and A. albopictus. Severe dengue is a leading cause of serious illness and death among children in some Asian and Latin American countries. There is no specific treatment for dengue/severe dengue, but early detection and access to proper medical care lowers fatality rates to below 1%. Chikungunya infections can also be severe, especially for young children and the elderly. However, therapeutics differ for the three diseases, and physicians require accurate diagnostic tools that can detect and distinguish between the viruses in order to determine the most appropriate treatments.
The Logix Smart ZDC Test Kit is intended for molecular biology applications to aid in the differentiation and diagnosis of Zika, dengue, and chikungunya in human serum and urine specimens. It is recommended for serum to be collected alongside a urine sample.
This product is for export only and is not for sale in the United States.
The Logix Smart ZDC Test was designed and validated as a real-time RT-PCR kit that targets and differentiates between conserved regions in the genomes of the three pathogens.
This assay is a single step reverse transcription real-time reaction that can be broken down into 3 stages: sample preparation, reverse transcription, and the polymerase chain reaction with real-time monitoring. The assay has an internal positive control (IPC) that also acts as an extraction control to monitor the extraction, amplification, and detection steps.